Minute Volume Viscometer
نویسندگان
چکیده
In the field of pharmaceutical research, injectable treatment therapy is currently one of the most highly examined methods of drug delivery. The continuation of this research is highly dependent on knowledge of fluid properties, specifically loss and storage modulus. Most drugs in the developmental stages of this method are extremely expensive and limited in quantity. Currently, devices that measure fluid properties require samples sizes larger than 150 μL. A device that would minimize the sample volume would be quite valuable to pharmaceutical companies. We have designed a device that will be able to quickly and accurately measure the loss and storage modulus of sample volumes of less than 20 μL. Three designs were considered throughout the planning of this project. One utilized polarized lenses with an alternating current to calculate the relative “brightness” of light through a sample liquid. A second method employed tuning forks vibrations as they propagate through a sample liquid to calculate waveform impedance. We have concluded that the optimal design for this project is one which calculates impedance of shear waves based on a loaded piezoelectric crystal.
منابع مشابه
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